Anti-PP2A Antibody, Catalytic subunit

Descrição detalhada : PP2A is a type 2 protein Ser/Thr phosphatase characterized by high activity against the alpha subunit of Phosphorylase Kinase and low sensitivity to Inhibitor-2. PP2A is distinguishable from PP2B/Calcineurin and PP2C by its partial activity in the absence of divalent cations, and its high sensitivity to Okadaic Acid. It is also thought to be the principal downmodulator of Ser/Thr kinase cascades. PP2A is a heterotrimer containing a structural subunit (A), a regulatory subunit (B), and a catalytic subunit (C). There are multiple isotypes (encoded by distinct genes) of the B subunit, grouped into three families: B/PR55, B'/PR61, and B''/PR72 . PTPA is a member of the B' family that is required for activation of PP2A by an undefined mechanism.
Sinónimos : Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, delta isoform, Delta isoform of regulatory subunit B56, protein phosphatase, Protein phosphatase 2, regulatory subunit B (B56), delta isoform, Protein phosphatase 2, regulatory subunit B
Armazenamento : -80°C
Embalagem : 1X1EA