Anti-PPAR alpha Antibody

Descrição detalhada : Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that can be activated by a variety of compounds including fibratus, thiazolidinediones, prostaglandins and fatty acids. Three PPAR subtypes, designated PPARalpha, PPARbeta (also designated PPARdelta) and PPARgamma, have been described. PPARs promote transcription by forming heterodimers with members of the retinoid X receptor (RXR) family of steroid receptors and binding to specific DNA motifs termed PPAR-response elements (PPREs). PPARalpha is abundant in primary hepatocytes where it regulates the expression of proteins involved in fatty acid metabolism. PPARbeta is the most widely distributed subtype and is often expressed at high levels. PPARgamma is predominantly seen in adipose tissue where it plays a critical role in regulating adipocyte differentiation.
Sinónimos : PPAR alpha
Armazenamento : -20°C
Embalagem : 1X1EA