Anti-Pro-neuregulin-1, membrane-bound isoform (NRG1 Antibody)

Descrição detalhada : Neuregulin isoforms have been classified as type I NRGs (isoforms with an Ig domain and a glycosylation domain, isoforms 1-8), type II NRGs (isoforms with an Ig domain but no glycosylation domain, isoform 9). Neuregulin Type I/II serve as direct ligands for ERBB3 and ERBB4 tyrosine kinase receptors that regulate development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. Type I isoforms are the predominant forms expressed in the endocardium. Type II is the major form in skeletal muscle cells, and is expressed in the spinal cord, brain, adult heart, placenta, lung, liver, kidney, and pancreas. Neuregulin-HBD refers to the heparin binding domain of Type I/II Neuregulin.
Sinónimos : Pro-neuregulin-1, membrane-bound isoform, Pro-NRG1, Neuregulin-1, Acetylcholine receptor-inducing activity, ARIA, Breast cancer cell differentiation factor p45, Glial growth factor, Heregulin, HRG, Neu differentiation factor, Sensory and motor neuron-der
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA