Anti-Protein Kinase Calpha antibody produced in rabbit

Descrição detalhada : PKC ? is a conventional isoform of Protein Kinase C (76-93 kD) and a member of serine/threonine (Ser/Thr) protein kinases. It is expressed ubiquitously in tissues and is the major isoform of PKC in fibroblasts. Stimulation and overexpression of PKC ? increases the growth rate of cells in culture. Anti-Protein Kinase C ? antibody is useful for studying expression of PKC ? in normal and neoplastic tissues. It is also useful for detecting PKC ? isoenzyme in brain tissue and cell extracts. Furthermore, it can be used in chemiluminescence detection systems to detect PKC ?. Rabbit anti-protein kinase c ? antibody reacts specifically with PKC ? (80 kD) of rat brain extract or NIH3T3 mouse fibroblast lysate., Anti-Protein Kinase Calpha is produced in rabbit using a synthetic peptide conjugated to keyhole limpet hemocyanin (KLH) as the immunogen. PKC is a phospholipid dependent enzyme, activated by the lipid 1,2-diacylglycerol (DAG), an intracellular second messenger produced from hydrolysis of inositol phospholipids, in response to a variety of hormones, growth factors, and neurotransmitters.
Sinónimos : Anti-PKCalpha
Armazenamento : -20C
Embalagem : 1X.2ML