Anti-Puma BH3 domain Antibody

Descrição detalhada : PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis
Sinónimos : BCL2 binding component 3, Bcl-2 binding component 3, p53 up-regulated modulator of apoptosis
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA