Anti-Rabbit IgG (whole molecule)-Alkaline Phosphatase antibody produced in goat

REF : A8025-.5ML
Marca : Sigma-Aldrich
Descrição :Anti-Rabbit IgG (whole molecule)-Alkaline Phosphatase antibody produced in goat affinity isolated antibody, buffered aqueous glycerol solution
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Descrição detalhada : IgGs are glycoprotein antibodies that modulate several immune responses. Rabbit IgGs against target proteins are often used as primary antibodies in various research applications. Thus, secondary anti-rabbit IgGs conjugated to a detectable substrate are useful tools for the analysis of target proteins. Goat Anti-Rabbit IgG (whole molecule)-Alkaline Phosphatase antibody binds to all rabbit Igs., Immunoglobulin G (IgG) is part of the immunoglobulin family and is widely expressed in the serum. It consists of a gamma (?) heavy chain in the constant (C) region. The monomeric structure of IgG consists of two identical heavy chains and two identical light chains with molecular weight of 50kDa and 25kDa, respectively. The primary structure of this antibody also contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and resides inside the chains. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named ?1, ?2, ?3, and ?4, respectively. Limited digestion using papain cleaves the antibody into three fragments, two of which are identical and contain the antigen-binding activity (Fab fragments). The third fragment known as fragment crystallizable (Fc).
Sinónimos : Goat Anti-Rabbit IgG (whole molecule)-AP
Armazenamento : 2-8C
Embalagem : 1X.5ML