Anti-Raf-1/c-Raf antibody, Mouse monoclonal

Descrição detalhada : Raf-1 is a serine/threonine kinase that is activated by tyrosine kinases and functions upstream of the MAPK-signaling pathway. Raf-1 inhibits Ras signaling and subsequently modulates cell proliferation and development. c-Raf expression has been linked to the pathogenesis of lung carcinoma., Monoclonal Anti-Raf-1/c-Raf (mouse IgG1 isotype) is derived from the RNP1 hybridoma produced by the fusion of mouse myeloma cells (NS1) and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to amino acids 334-345 of human Raf-1.
Sinónimos : Anti-CMD1NN; Anti-CRAF; Anti-NS5; Anti-Raf-1; Anti-c-Raf
Armazenamento : -20C
Embalagem : 1X200UL