Anti-RNF8 antibody produced in rabbit

Descrição detalhada : Ring finger protein 8 (RNF8) is an E3 ubiquitin ligase which ubiquitinates proteins for degradation by proteosomes. RNF8 is involved in DNA double-strand break (DSB) repair, wherein RNF8 and RNF168 control the recruitment of 53BP1 to DNA damage sites and ubiquitination of histone-2A. RNF8 also mediates chromatin decondensation to create a local chromatin environment that is permissive to the assembly of checkpoint and repair machineries at DNA lesions.
Sinónimos : Anti-FLJ12013; Anti-KIAA0646; Anti-Ring finger protein 8
Armazenamento : -20C
Embalagem : 1X100UL