Anti-Rubicon antibody, Mouse monoclonal

Descrição detalhada : Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (Rubicon) also known as Beclin-1 associated RUN domain containing protein (Baron) or KIAA0226, is a negative regulator of endosomes maturation and endocytic trafficking.1-2 Rubicon knockdown studies showed enhanced autophagosome maturation and endocytosis.1 It also have a critical role in the LC3-associated phagocytosis (LAP) a noncanonical autophagy process which can be induced through the activation of extracellular receptor by different stimulators including pathogens, immune complexes and dying cells.4-5
Sinónimos : Beclin-1 associated RUN domain containing protein; KIAA0226; RUBCN; Run domain Beclin-1-interacting and cysteine-rich domain-containing protein; SCAR15
Armazenamento : -20C
Embalagem : 1X25UL