Anti-SnoN Antibody

Descrição detalhada : The Ski family of oncogenes includes Ski and Sno (Ski-related novel gene, or Ski-like). Ski family members are nuclear proteins that form homodimers and heterodimers, bind to DNA and function as transcriptional activators and repressors. The Ski proteins regulate TGFß induced gene-specific transcriptional activation by effectively repressing Smad activity and, thereby, inhibit TGFß induced cell growth and extracellular matrix production. Recently, SnoN has been shown to maintain pluripotency through selective repression of mesendodermal genes in human ES cells.
Sinónimos : Ski-like protein, Ski-related oncogene, Ski-related protein, SnoN
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA