Anti-TGN46 antibody produced in rabbit

Descrição detalhada : TGN46 (Trans-Golgi network protein, 46 kDa), the human homologue of rat TGN38, is a resident integral membrane protein of the trans-Golgi network (TGN) that cycles constitutively between the TGN and the plasma membrane, returning via endosomes. The TGN is the major sorting compartment of the secretory pathway for proteins, lipids and membrane traffic. TGN46 is a heavily glycosylated protein, probably involved in regulating membrane traffic to and from the TGN. TGN46 contains a signal peptide, lumenal domain, membrane-spanning domain, and cytoplasmic domain. The membrane spanning region and cytoplasmic tail contain the retention and retrieval signals, respectively for localization in the TGN. TGN46 is widely expressed., Anti-TGN46 recognizes human trans-golgi network protein 2 (TGN46). Detection of the TGN46 band by immunoblotting is specifically inhibited by the immunizing peptide.
Sinónimos : Anti-MGC14722; Anti-TGN38 homolog; Anti-TGN48; Anti-TGN51; Anti-TGOLN2; Anti-TTGN2; Anti-Trans-Golgi network integral membrane protein 2 precursor; Anti-Trans-Golgi network protein TGN51; Anti-Trans-golgi network protein 2
Armazenamento : -20C
Embalagem : 1X200UL