Anti-Tyrosine Hydroxylase Antibody, clone 10F8.2

Descrição detalhada : Tyrosine 3-monooxygenase (EC 1.14.16.2; UniProt P04177; also known as TH, Tyrosine 3-hydroxylase) is encoded by the Th gene (Gene ID 25085) in rat species. Tyrosine hydroxylase plays an important role in the physiology of adrenergic neurons. It is the first and rate-limiting enzyme involved in the biosynthesis of the catecholamines, dopamine and norepinephrine, from tyrosine. TH is, therefore, a useful marker for dopaminergic and noradrenergic neurons. TH enzymatic activity requires ferrous ions as cofactor and is believed to be regulated by phosphorylation. Six human TH isoforms exist as a result of alternative splicing (UniProt P07101-1 through P07101-6).
Sinónimos : TH, Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, Tyrosine Hydroxylase
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA