Anti-Ubiquitin Antibody, Lys63-Specific, clone Apu3, rabbit monoclonal

Descrição detalhada : Polyubiquitin chains linked through the Lys63 residue of ubiquitin (Ub) are associated with nonproteolytic functions such as signal transduction. Lys63-linked polyUb chains connect components of NFkappaB signaling in a highly regulated manner, and genetic evidence indicates the involvement of Lys63-linked Ub chains in stress response and DNA repair. Research in yeast has suggested Lys63-linked Ub chains stimulate endocytosis.In contrast, polyubiquitin chains linked through the Lys48 residue of ubiquitin are most commonly associated with proteins targeted for proteosomal degradation., DI-UBIQUITIN PROTEIN AVAILABLE!Di-Ubiquitin (Lys63-linked) Recombinant Protein (17-10388)
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA