Anti-WASH1 antibody, Mouse monoclonal

Descrição detalhada : Monoclonal Anti-WASH1 (mouse IgG1 isotype) is derived from the hybridoma WASH1-27 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to an internal region of human WASH1. WASH1 (Wiskott-Aldrich Syndrome Protein and SCAR Homolog), a new member of the Wiskott?Aldrich Syndrome protein (WASP) family. Similar to other WASP family members, it contains a C-terminal for ?WH2, connecting and acidic? (WCA) domain that binds to actin and the Arp2/3 complex. In addition, WASH1 also contains a short proline-rich region, a unique N-terminal domain termed WASH-homology domain (WAHD1), and a tubulin-binding region. Through its WAHD1 region, it interacts with family with sequence similarity 21 (FAM21), a protein that links WASH1 to endosomes. WASH1 forms part of a multiprotein complex composed of FAM21, KIAA1033 strumpellin and WASH-interacting protein (SWIP) and coiled coil domain containing 53 (CCDC53).
Sinónimos : Anti-CXYorf1-like protein on chromosome 9; Anti-FAM39E; Anti-WAS protein family homolog 1; Anti-WASH; Monoclonal Anti-WASH1 antibody produced in mouse
Armazenamento : -20C
Embalagem : 1X200UL