Anti-Yes-associated protein (YAP1) Antibody, clone 4D11.1

Descrição detalhada : The YAP1 gene encodes a protein that binds to the SH3 (Src homology 3) domain of the Yes proto-oncogene product. As a transcriptional regulator, it can act as a coactivator and a corepressor, and serves as a critical downstream regulatory target in the Hippo signaling pathway. Additionally, it plays a critical role in regulating organ size and in tumor suppression by restricting proliferation and promoting apoptosis. The human YAP1 gene is well conserved among higher eukaryotes, but may not be conseved in yeast. Yes-associated protein expression is almost ubiquitous in adult human tissues, but is not detectable in peripheral blood leukocytes.
Sinónimos : Yorkie homolog, Yes-associated protein, Yap65
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA