Autocamtide-2 Related Inhibitory Peptide II, Cell-permeable – Calbiochem

REF : 189485-1MG
Marca : Sigma-Aldrich
Descrição :Autocamtide-2 Related Inhibitory Peptide II, Cell-permeable - Calbiochem The Autocamtide-2 Related Inhibitory Peptide II, Cell-permeable controls the biological activity of calmodulin-dependent protein kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Descrição detalhada : A highly specific, potent, cell-permeable calmodulin-dependent protein kinase II (CaMKII) inhibitor that contains the Antennapedia transport peptide sequence fused to the amino terminus of AIP-II (Cat. No. 189484)., A highly specific, potent, cell-permeable calmodulin-dependent protein kinase II (CaMKII) inhibitory peptide that contains the Antennapedia transport peptide sequence fused to the N-terminus of autocamtide inhibitory peptide-II (AIP-II) (Cat. No. 189484). AIP-II is an AIP analog where Ala3 and Val10 are replaced by Lys and Phe residues. AIP-II is reported to be more potent than CaMK-(281-302/Ala286) and KN-93 (Cat. No. 422708). Inhibits by binding to the autophosphorylation site, which is distinct from the exogenous substrate-binding site.
Sinónimos : Autocamtide-2 Related Inhibitory Peptide II, Cell-permeable - Calbiochem; Ant-A3K/V10F-AIP, Ant-AIP-II, Ac-RQIKIWFQNRRMKWKKKKKLRRQEAFDAL-OH
Fórmula molecula r: C177H291N57O39S
Armazenamento : -20C
Embalagem : 1X1MG