BAPTA, Tetrasodium Salt

Descrição detalhada : Ca2+-chelator exhibiting a 105-fold greater affinity for Ca2+ (110 nM) than for Mg2+. After BAPTA complexes with Ca2+, the UV spectrum shifts from 254 to 279 nm at pH >6.0. Useful for spectrophotometric monitoring of extracellular Ca2+ levels, especially transient phenomena, because of its insensitivity to pH. Has been used for the measurement and control of Ca2+ levels in eggs, chromaffin cells, muscle cells, retinal cells, and pancreatic cells. In conjunction with certain formazan dyes, BAPTA can be used in a colorimetric assay for Mg2+. Has neuroprotective effects in vitro against excitotoxic damage and spontaneous recurrent seizures, such as epilepsy.
Sinónimos : BAPTA, Tetrasodium Salt; 1,2- bis( o-Aminophenoxy)ethane-N,N,N?,N?-tetraacetic Acid, 4Na; 1,2-bis(o-Aminophenoxy)ethane-N,N,N?,N?-tetraacetic Acid, 4Na
Fórmula molecula r: C22H20N2O10 · 4Na
Armazenamento : -20C
Embalagem : 1X1GM