Bax Channel Blocker – CAS 335165-69-0 – Calbiochem

Descrição detalhada : A cell-permeable dibromocarbazole-piperazinyl derivative that displays anti-apoptotic properties. Reported to effectively block Bid-induced cytochrome c release from HeLa cell mitochondria (~80% inhibition at 5 microM) by inhibiting Bax channel activity., A cell-permeable dibromocarbazolo-piperazinyl derivative that displays anti-apoptotic properties. Effectively blocks Bid-induced cyctochrome c release from HeLa cell mitochondria (~80% inhibition at 5 microM) by inhibiting Bax channel-forming activity (IC50 = 520 nM in a liposome channel assay).
Sinónimos : Bax Channel Blocker - CAS 335165-69-0 - Calbiochem; (+/-)-1-(3,6-Dibromocarbazol-9-yl)-3-piperazin-1-yl-propan-2-ol, iMAC1
Fórmula molecula r: C19H21Br2N3O
Armazenamento : 2-8C; 2-8C; 2-8C; 2-8C
Embalagem : 1X5MG