(+)-Bicuculline – CAS 485-49-4 – Calbiochem

Descrição detalhada : A potent allosteric antagonist of vertebrate GABAA receptors. Blocks GABAA-induced chloride currents in cultured neurons (IC50 = 740 nM). Shown to increase blood pressure in spontaneously hypertensive rats and cause convulsion in experimental animals. Also, increases the amplitude of spontaneous colonic contractions.
Sinónimos : (+)-Bicuculline - CAS 485-49-4 - Calbiochem; GABA A Receptor Antagonist, Bicuculline
Fórmula molecula r: C20H17NO6
Armazenamento : -20C
Embalagem : 1X1EA