(+/-)-Blebbistatin – CAS 674289-55-5 – Calbiochem

Descrição detalhada : A cell-permeable compound that acts as a selective, potent, and reversible inhibitor of non-muscle myosin II. Inhibits the ATPase and gliding motility of human platelets (<=100 µM) without affecting myosin light chain kinase (MLCK) activity. Has been shown to block cell blebbing and to rapidly disrupt directed cell migration and cytokinesis in vertebrate cells. Does not disrupt mitosis or affect contractile ring assembly., A cell-permeable compound that acts as a selective, potent, and reversible inhibitor of nonmuscle myosin II. Inhibits the ATPase and gliding motility of human platelets (<= 100 µM) without affecting myosin light chain kinase (MLCK) activity. Has been shown to block cell blebbing and to rapidly disrupt directed cell migration and cytokinesis in vertebrate cells. Does not disrupt mitosis or affect contractile ring assembly. A 50 mM (5 mg/342 µl) solution of (+/-)-Blebbistatin (Cat. No. 203389) in 90% DMSO is also available.
Sinónimos : (+/-)-Blebbistatin - CAS 674289-55-5 - Calbiochem
Fórmula molecula r: C18H16N2O2
Armazenamento : -20C
Embalagem : 1X5MG