BTS – CAS 1576-37-0 – Calbiochem

Descrição detalhada : A potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 = ~ 5 µM) and reversibly blocks the gliding motility. It also weakens myosin's interaction with F-actin. Much less effective in suppressing contraction in rat myocardial or rabbit slow twitch muscle and has no effect on platelet myosin II., An aryl sulphonamide that acts as a potent inhibitor of Ca2+-stimulated myosin S1 actin-stimulated ATPase activity (IC50 = ~5 µM). Also blocks actin-stimulated ATPase activity with similar potency (IC50 = 5 µM). Reversibly blocks gliding motility of skeletal muscle myosin (IC50<2 µM). Less effective in suppressing contraction in rat myocardial and rabbit slow twitch muscle compared to skeletal muscle. Does not inhibit platelet myosin II.
Sinónimos : BTS - CAS 1576-37-0 - Calbiochem; N-Benzyl- p-toluenesulphonamide; N-Benzyl-p-toluenesulphonamide
Fórmula molecula r: C14H15NO2S
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X5MG