C-Reactive Protein, Human Serum, High Purity

REF : 236603-100UG
Marca : Sigma-Aldrich
Descrição :C-Reactive Protein, Human Serum, High Purity C-Reactive Protein, Human Serum, High Purity, CAS 9007-41-4, is a major acute-phase plasma protein. Useful as a calibration standard for assays of CRP and as an antigen for production of antisera.
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Descrição detalhada : Native C-reactive protein highly purified from human serum. CRP is a major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca2+-dependent binding to a variety of substrates. Important in diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. ~21 kDa) aggregates as a cyclic pentamer. Intended for use as a calibration standard for assays of CRP, for structural and functional studies, and as an antigen for production of antisera.Calibrated by electroimmunoassay against WHO reference standard or equivalent., No reaction in ODD and Laurell electroimmunoassay against polyvalent antiserum to normal human serum, antiserum to pooled effusion fluids and monospecific antiserum to human IgG., M.W. 23,000 (monomer); 115,000 (pentamer).
Sinónimos : C-Reactive Protein, Human Serum, High Purity; CRP
Armazenamento : -70C
Embalagem : 1X100UG