Calmodulin Kinase IINtide – Calbiochem

Descrição detalhada : A potent and specific inhibitor of CaMK II (IC50 = 50 nM for both the total and Ca2+-independent CaMK II activity). Exhibits inhibitory activity across converged species, including rat brain, goldfish brain, and Drosophila (IC50 range 100-400 nM). Does not affect the activities of CaMK I, CaMK IV, CaMKK, PKA, or PKC. The peptide sequence corresponds to the inhibitory domain of CaMK IIN., A potent and specific inhibitor of calmodulin kinase II (CaM-KII) (IC50 = 50 nM for both total and Ca2+-independent activities of CaM-KII). Does not affect the activities of CaM-KI, CaM-KIV, CaM-KK, PKA, or PKC. The peptide sequence corresponds to the inhibitory domain of the inhibitory protein, CaM-KIIN. A cell-permeable version is available under Cat. No. 208921.
Sinónimos : Calmodulin Kinase IINtide - Calbiochem; KRPPKLGQIGRAKRVVIEDDRIDDVLK-OH
Fórmula molecula r: C136H240N44O39
Armazenamento : -20C
Embalagem : 1X1MG