Calpeptin

REF : C8999-5MG
Marca : Sigma-Aldrich
Descrição :Calpeptin >=98% (HPLC)
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Descrição detalhada : Calpeptin (Z-Leu-nLeu-H) is a cell permeable, peptide aldehyde inhibitor. It is more sensitive to calpain I compared to other inhibitors, such as Z-Leu-Met-H and leupeptin. Calpeptin stimulates neurite elongation in differentiating pheochromocytoma (PC12) cells. Calpeptin decreases microgliosis, astrogliosis, axonal damage and neuron and oligodendrocyte death in experimental autoimmune encephalomyelitis (EAE) spinal cord. Therefore, it can be considered as a potent therapeutic for treating EAE and multiple sclerosis (MS).
Sinónimos : N-Benzyloxycarbonyl-L-leucylnorieucinal; Z-Leu-Nle-CHO
Fórmula molecula r: C20H30N2O4
Armazenamento : -20C
Embalagem : 1X5MG