Calyculin A, Discodermia calyx – CAS 101932-71-2 – Calbiochem

REF : 208851-10UG
Marca : Sigma-Aldrich
Descrição :Calyculin A, Discodermia calyx - CAS 101932-71-2 - Calbiochem Calyculin A, CAS 101932-71-2, is a cell-permeable inhibitor of protein phosphatase 2A (IC?? = 0.5-1 nM) and protein phosphatase 1 (PP1; IC?? = 2 nM).
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Descrição detalhada : A cell-permeable inhibitor of protein phosphatase 2A (PP2A; IC50 = 0.5-1 nM) and protein phosphatase 1 (PP1; IC50 = 2 nM). A non-phorbol ester type tumor promoter that induces oxidative DNA damage. Selectively increases the efficacy of AMPA receptor-mediated synaptic transmission at excitatory synapses. Also known to prevent gamma-radiation induced apoptosis in Burkitt's lymphoma cell line BM13674. Also available as a 100 µM solution in DMSO (Cat. No. 508226).
Sinónimos : Calyculin A, Discodermia calyx - CAS 101932-71-2 - Calbiochem
Fórmula molecula r: C50H81N4O15P
Armazenamento : -20C
Embalagem : 1X1EA