Camptothecin, 10-Hydroxy-, Camptotheca acuminata – CAS 64439-81-2 – Calbiochem

Descrição detalhada : A cell-permeable, powerful DNA topoisomerase I inhibitor. Reduces DNA synthesis in vitro in murine hepatoma cells. Inhibits the proliferation of hepatoma HepG2, Bcl-7402 and Bcl-7404 cells in a dose-dependent manner. Has selective inhibitory effect on the phosphorylation of histones H1 and H3, but is less effective on other histones., A cell-permeable powerful DNA topoisomerase I inhibitor. Reduces DNA synthesis in vitro in murine hepatoma cells. Has selective inhibitory effect on the phosphorylation of histone H1 and H3, but less effect on other histones.
Sinónimos : Camptothecin, 10-Hydroxy-, Camptotheca acuminata - CAS 64439-81-2 - Calbiochem; 10-Hydroxycamptothecin, HCPT
Fórmula molecula r: C20H16N2O5
Armazenamento : 2-8C; 2-8C
Embalagem : 1X25MG