Cas9-D10A Nickase Protein

REF : CAS9D10APR-250UG
Marca : Sigma-Aldrich
Descrição :Cas9-D10A Nickase Protein from Streptococcus pyogenes with D10A mutation, recombinant, expressed in E. coli, 1X NLS
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Descrição detalhada : Cas9 (CRISPR (clustered regularly interspaced short palindromic repeats)-associated protein-9 nuclease) nickase creates double-stranded breaks through two nuclease domains, named RuvC and HNH., Recombinant Cas9-D10A Nickase protein from Streptococcus pyogenes (~160 KD) is a ready-to-use reagent for genome engineering experiments. When combined with target-specific paired guide RNAs, S. pyogenes Cas9-D10A nickase will act as a targeted nuclease suitable for transfection of cell cultures and for the accelerated development of genetically-modified animals via one-cell embryo injection.
Sinónimos : Cas9 Nickase; Cas9D10A; Nickase Cas9
Armazenamento : -20C
Embalagem : 1X250UG