Cas9 Protein

REF : CAS9PROT-250UG
Marca : Sigma-Aldrich
Descrição :Cas9 Protein from Streptococcus pyogenes, recombinant, expressed in E. coli, 1X NLS
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Descrição detalhada : Recombinant Cas9 protein from Streptococcus pyogenes (~160 KD) is a ready-to-use reagent for genome engineering experiments. When combined with target-specific guide RNAs, wild type Streptococcus pyogenes Cas9 protein will act as a targeted nuclease suitable for transfection of cell cultures and for the accelerated development of genetically-modified animals via one-cell embryo injection., CAS9, also known as cas5 and csn1, is the signature gene of the type II clustered regularly interspaced short palindromic repeats (CRISPR)-RuvC (RNase H-like fold) cas system. CAS9 contains 1388 amino acids. This protein is predicted to contain a RuvC/ ribonuclease (RNase) H domain involved in crRNA maturation and McrA/HNH signature domain involved in the DNA degradation step.
Sinónimos : Cas9; SpCas9; SpyCas9
Armazenamento : -20C
Embalagem : 1X250UG