Caspase-1 Inhibitor II – CAS 178603-78-6 – Calbiochem

REF : 400012-5MG
Marca : Sigma-Aldrich
Descrição :Caspase-1 Inhibitor II - CAS 178603-78-6 - Calbiochem The Caspase-1 Inhibitor II, also referenced under CAS 178603-78-6, controls the biological activity of Caspase-1. This small molecule/inhibitor is primarily used for Cancer applications.
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Descrição detalhada : Interleukin-1beta converting enzyme (ICE) is a cysteine protease that cleaves the IL-1beta precursor to mature IL-1beta. Caspase-1 inhibitor II is a cell-permeable, irreversible inhibitor of Caspase-1, Caspase-4, and Caspase-5. Inhibits CPP32/Apopain at a much higher concentration. Inhibits Fas-mediated apoptosis and acidic sphingomyelinase activation., A cell-permeable and irreversible inhibitor of caspase-1 (Ki = 760 pM), caspase-4, and caspase-5. Inhibits Fas-mediated apoptosis and acidic sphingomyelinase activation.
Sinónimos : Caspase-1 Inhibitor II - CAS 178603-78-6 - Calbiochem; IL-1beta Converting Enzyme (ICE) Inhibitor II, Ac-YVAD-CMK
Fórmula molecula r: C24H33ClN4O8
Armazenamento : -20C
Embalagem : 1X5MG