Caspase-8 Inhibitor II – Calbiochem

REF : 218759-250UG
Marca : Sigma-Aldrich
Descrição :Caspase-8 Inhibitor II - Calbiochem The Caspase-8 Inhibitor II controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications.
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Descrição detalhada : A potent, cell-permeable, and irreversible inhibitor of caspase-8 (MACH, FLICE, Mch5). Also inhibits granzyme B., A potent, cell-permeable, and irreversible inhibitor of caspase-8 and granzyme B. Effectively inhibits influenza virus-induced apoptosis in HeLa cells. Also inhibits granzyme B. When using with purified native or recombinant enzyme, pretreatment with an esterase is required. A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218840) in DMSO is also available.
Sinónimos : Caspase-8 Inhibitor II - Calbiochem; Z-IE(OMe)TD(OMe)-FMK, Granzyme B Inhibitor III
Fórmula molecula r: C30H43FN4O11
Armazenamento : -20C
Embalagem : 1X250UG