Cathepsin K Inhibitor III – Calbiochem

REF : 219381-1MG
Marca : Sigma-Aldrich
Descrição :Cathepsin K Inhibitor III - Calbiochem The Cathepsin K Inhibitor III controls the biological activity of Cathepsin K. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
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Descrição detalhada : A cell-permeable, potent, selective, reversible inhibitor of cathepsin K (Ki,app = 9.7 nM). At higher concentrations also inhibits the activities of cathepsin L, cathepsin B, and papain (Ki,app = 120 nM, 5.1 mM, and 2.3 µM, respectively). Reported to completely block cathepsin K activity in primary human synovial fibroblast cultures at a concentration of 1 µM., A cell-permeable peptidyl bis-carbohydrazide compound that acts as a potent, selective, and reversible inhibitor of cathepsin K (Ki,app = 9.7 nM). At higher concentrations, also inhibits the activities of cathepsin L, cathepsin B, and papain (Ki,app = 120 nM, 5.1 µM, and 2.3 µM, respectively). Completely blocks cathepsin K activity in primary human synovial fibroblast cultures at 1 µM.
Sinónimos : Cathepsin K Inhibitor III - Calbiochem; Inhibitor I, 1-(N-Benzyloxycarbonyl-leucyl)-5-(phenylalanyl-leucyl)carbohydrazide, Z-L-NHNHCONHNH-LF-NH?
Fórmula molecula r: C30H43N7O6
Armazenamento : -20C
Embalagem : 1X1MG