Cathepsin L Inhibitor, CAA0225 – Calbiochem

Descrição detalhada : An epoxysuccinyl peptide highly selective for rat liver cathepsin L (IC50 = 1.9 nM), while exhibiting little to no effect on rat liver cathepsin B at concentrations higher than 1000-5000 nM, in vitro. During autophagy, it has been shown through immunoblotting that CAA0225 (10 µg/ml) effectively inhibits the degradation of LC3-II and GABARAP compared to control, in nutrient-deprived HeLa and Huh-7 cells.
Sinónimos : Cathepsin L Inhibitor, CAA0225 - Calbiochem
Fórmula molecula r: C28H29N3O5
Armazenamento : -20C
Embalagem : 1X1MG