Cerulenin, Cephalosporium caerulens – CAS 17397-89-6 – Calbiochem

Descrição detalhada : An antifungal antibiotic that inhibits sterol and fatty acid biosynthesis. In fatty acid synthesis, reported to bind in equimolar ratio to beta-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. Also shown to inhibit feeding and induce dramatic weight loss in mice., An anti-fungal antibiotic that inhibits fatty acid biosynthesis by binding, in equimolar ratio, to beta-keto-acyl-ACP synthase. Also inhibits sterol synthesis by blocking the activity of HMG-CoA synthetase activity. Systemic and intracerebroventricular of this compound reduces feeding and induces weight loss.
Sinónimos : Cerulenin, Cephalosporium caerulens - CAS 17397-89-6 - Calbiochem
Fórmula molecula r: C12H17NO3
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X5MG