Cisplatin – CAS 15663-27-1 – Calbiochem

Descrição detalhada : A platinum coordination complex with potent anti-neoplastic activity. Induces apoptosis in cancer cells, possibly via caspase-3 activation. Reported to sensitize glioma cells to TNF-alpha-induced apoptosis. Note: Athough highly soluble in DMSO, Cisplatin is reported to be rendered inactive due to ligand displacement by the nucleophilic sulfur of DMSO. Sodium chloride solution in water (154 mM NaCl with or without 10 mg/ml mannitol) or PBS (with 140 mM NaCl) is recommended for solubilization prior to culture treatment., A platinum coordination complex with potent antineoplastic activity.Note: Athough highly soluble in DMSO, Cisplatin is reported to be rendered inactive due to ligand displacement by the nucleophilic sulfur of DMSO. Sodium chloride solution in water (154 mM NaCl with or without 10 mg/ml mannitol) or PBS (with 140 mM NaCl) is recommended for solubilization prior to culture treatment.
Sinónimos : Cisplatin - CAS 15663-27-1 - Calbiochem; CPDC, DDP, cis-Diaminedichloroplatinum
Fórmula molecula r: Pt(NH3)2Cl2
Armazenamento : 2-8C; 2-8C
Embalagem : 1X50MG