Congo Red, High Purity – CAS 573-58-0 – Calbiochem

Descrição detalhada : An amyloidophylic dye that specifically stains stacked beta sheet aggre-gates. Useful for staining and visual detection of amyloid deposits in nerve tissue. Binds to amyloid fibrils but not to non-polymerized amyloid peptide. Inhibits the accumulation of the scrapie-associated, protease-resistant isoform of protein PrP without affecting the normal isoform possibly through overstabilization of the conformation. It is also shown to inhibit Pot1 Binding to Telomeric DNA., An amyloidophylic dye that specifically stains stacked beta sheet aggregates. Useful for staining and visual detection of amyloid deposits. Does not bind to non-polymerized amyloid peptide. Inhibits the accumulation of the scrapie-associated, protease-resistant isoform of protein PrP without affecting the metabolism of the normal isoform. It is also shown to inhibit Pot1 Binding to Telomeric DNA.
Sinónimos : Congo Red, High Purity - CAS 573-58-0 - Calbiochem; 3,3?-[(1,1?-Biphenyl)-4,4?-diylbis(azo)]bis(4-amino-1-naphthalenesulfonic Acid) 2Na
Fórmula molecula r: C32H22N6O6S2 · 2Na
Armazenamento : 15-25C
Embalagem : 1X500MG