COX-2 Inhibitor V, FK3311 – CAS 116686-15-8 – Calbiochem

REF : 236015-5MG
Marca : Sigma-Aldrich
Descrição :COX-2 Inhibitor V, FK3311 - CAS 116686-15-8 - Calbiochem The COX-2 Inhibitor V, FK3311, also referenced under CAS 116686-15-8, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications.
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Descrição detalhada : A cell-permeable and orally available sulfonanilide that acts as a COX-2-selective non-steroidal anti-inflammatory drug (NSAID). Shown to exhibit 500-fold greater potency in inhibiting the LPS-induced (IC50 = 316 nM in human mononuclear cells) than the non-induced/constitutive (IC50 = 160 µM in human platelets) TxB2 production in vitro and effectively alleviate warm ischemia-reperfusion injury in the canine liver and rat lung in vivo.
Sinónimos : COX-2 Inhibitor V, FK3311 - CAS 116686-15-8 - Calbiochem; 4?-Acetyl-2?-(2,4-Difluorophenoxy)methanesulfonanilide
Fórmula molecula r: C15H13F2NO4S
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X5MG