CUDC 101
REF : EPS003-5MG
Marca : Sigma-Aldrich
Descrição :CUDC 101 A potent inhibitor of HDACs and receptor tyrosine kinases
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Categoria : Molecular Biology Specialties
Descrição detalhada : A potent multitargeted inhibitor of histone deacetylase (HDAC) and the receptor kinases epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), with IC50 values of 4.4, 2.4, and 15.7 nM, respectively.Displays potent antiproliferative and proapoptotic activities against cultured and implanted tumor cells that are sensitive or resistant to several approved single-targeted drugs.
Sinónimos : 7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide; Heptanamide, 7-[[4-[(3-ethynylphenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-N-hydroxy
Fórmula molecula r: C24H26N4O4
Armazenamento : -20C
Embalagem : 1X5MG
Sinónimos : 7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide; Heptanamide, 7-[[4-[(3-ethynylphenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-N-hydroxy
Fórmula molecula r: C24H26N4O4
Armazenamento : -20C
Embalagem : 1X5MG