D-erythro-Sphingosine, Free Base, High Purity – CAS 123-78-4 – Calbiochem

Descrição detalhada : Highly purified preparation of bovine brain sphingosine containing >99% of the erythro isomer., Highly purified preparation of bovine brain sphingosine containing >99% of the erythro isomer. A potent, cell-permeable, reversible, and selective inhibitor of protein kinase C (PKC; IC50 = 2.8 µM) and insulin receptor tyrosine kinase. PKC inhibition is competitive with respect to diacylglycerol, phorbol dibutyrate, and Ca2+. Does not affect the activity of myosin light chain kinase and protein kinase A. Induces apoptosis in human leukemia HL-60 cells. Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.
Sinónimos : D-erythro-Sphingosine, Free Base, High Purity - CAS 123-78-4 - Calbiochem; Cerebroside, trans-D- erythro-2-Amino-4-octadecene-1,3-diol, Ceramide; Cerebroside, trans-D-erythro-2-Amino-4-octadecene-1,3-diol, Ceramide
Fórmula molecula r: C18H37NO2
Armazenamento : -20C
Embalagem : 1X10MG