Dde-Lys(Fmoc)-OH

Descrição detalhada : Quasi-orthogonally-protected Lys derivative. The Fmoc group can be removed selectively by treatment with piperidine; the Dde group is cleaved with 2% hydrazine in DMF [1]. When removing Dde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group [2].Also available Fmoc-Lys(Dde)-OH 852057.This derivative has been employed in Fmoc SPPS to facilitate the introduction of biotin to the side-chain of lysine [3].The product number for this product was previously 04-12-5201.To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
Sinónimos : Dde-Lys(Fmoc)-OH; N-alpha-1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-N-epsilon-Fmoc-L-lysine
Fórmula molecula r: C31H36N2O6
Armazenamento : 15-25C
Embalagem : 1X1EA