E-Cadherin/Fc Chimera from mouse

Descrição detalhada : E (epithelial)-cadherin is a type I classical cadherin, which exists as a dimer. It has an ectodomain made of five extracellular cadherin-like (EC) domains, connected by conserved linker regions, which are calcium-binding in nature. It spans the membrane once, and contains a cytoplasmic region. It is a glycoprotein, and in humans has a molecular weight of 120kDa. It binds to catenin and cytoskeletal protein with its C-terminal domain., Extracellular domain of mouse E-Cadherin (amino acids 1-709) fused to the carboxy-terminal 6X histidine tagged Fc region of human IgG1.
Sinónimos : L-CAM; Arc-1; Cell-CAM120/80; Epithelial cadherin; Uvomorulin
Armazenamento : -20C
Embalagem : 1X50UG