Emetine, Dihydrochloride – CAS 316-42-7 – Calbiochem

Descrição detalhada : Principle alkaloid of ipecac, isolated from the ground roots of Uragoga ipecacuanha. Irreversibly blocks protein synthesis in eukaryotes by inhibiting the movement of ribosomes along the mRNA. Induces hypotension by blocking adrenoreceptors. Inhibits cytometric analysis of DNA replication at the early S phase. Also identified as a specific inhibitor of HIF-2alpha protein stability and transcriptional activity (IC50 <=1 µM., Principal alkaloid of ipecac, isolated from the ground roots of Uragoga ipecacuanha. Irreversibly blocks protein synthesis in eukaryotes by inhibiting the movement of ribosomes along the mRNA. Induces hypotension by blocking adrenoreceptors. Interferes with cytometric analysis of DNA replication at the early S phase. Also identified as a specific inhibitor of HIF-2alpha protein stability and transcriptional activity (IC50 <=1 µM.
Sinónimos : Emetine, Dihydrochloride - CAS 316-42-7 - Calbiochem; 6?,7?,10,11-Tetramethoxyemetan, 2HCl
Fórmula molecula r: C29H40N2O4 · 2HCl
Armazenamento : 2-8C; 2-8C; 2-8C; 2-8C
Embalagem : 1X250MG