Epidermal Growth Factor, human, animal component free

Descrição detalhada : Epidermal Growth Factor (EGF) is a small mitogenic polypeptide (?6 kDa), which is present in many mammalian species and is distributed throughout a wide number of tissues and body fluids.† Human EGF is identical to ?-urogastrone, a polypeptide which was recognized and isolated on the basis of its ability to inhibit gastric acid secretion.† EGF is a member of a growth factor family, which is characterized by the presence of 6 conserved cysteine motifs that form three disulfide bonds. The location of 3 intrachain disulfide bonds in recombinant human EGF is identical to that of mouse EGF.† EGF is homologous to a sequence contained in a 19 kDa protein of vaccinia virus,† which appears to utilize the EGF receptor to gain entry into cell† EGF is mitogenic for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.†, Epidermal growth factor (EGF) is synthesized in Henle?s loop and the distal convoluted tubule in the kidney. It is also produced in salivary glands and duodenum.
Sinónimos : Epidermal Growth Factor human; EGF
Armazenamento : -20C
Embalagem : 1X500UG