ErbB2 Inhibitor II – CAS 928207-02-7 – Calbiochem

REF : 324732-5MG
Marca : Sigma-Aldrich
Descrição :ErbB2 Inhibitor II - CAS 928207-02-7 - Calbiochem The ErbB2 Inhibitor II, also referenced under CAS 928207-02-7, controls the biological activity of ErbB2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Descrição detalhada : A cell-permeable triazole compound that targets the ATP-binding site of erbB2/HER2 and reduces the phosphorylation of erbB2 in MDA-MB-453 cells (IC50 = 6.6 µM), but not that of the overexpressed erbB1 in MDA-MB-468 cells even at concentrations as high as 100 µM. Shown to suppress MDA-MB-453 growth with an IC50 of 30.9 µM.
Sinónimos : ErbB2 Inhibitor II - CAS 928207-02-7 - Calbiochem; 4-(3-Phenoxyphenyl)-5-cyano-2H-1,2,3-triazole
Fórmula molecula r: C15H10N4O
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X5MG