Fucosyltransferase Inhibitor, 2F-Peracetyl-Fucose – Calbiochem
REF : 344827-10MG
Marca : Sigma-Aldrich
Descrição :Fucosyltransferase Inhibitor, 2F-Peracetyl-Fucose - Calbiochem 2F-Peracetyl-Fucose is a cell-permeable fluorinated fucose derivative that acts as an inhibitor of fucosyltransferases following its uptake and metabolic transformation into a GDP-fucose mimetic.
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Categoria : Small Molecules
Descrição detalhada : A cell-permeable fluorinated fucose derivative that acts as an inhibitor of fucosyltransferases following its uptake and metabolic transformation into a GDP-fucose mimetic. Treatment of HL-60 cells with this inhibitor shows complete abolition of Lewis-X and SLex within 3 days. Also abolishes P-selectin binding and exhibits faster rolling cells on E-selectin and P-selectin coated surfaces. Does not affect cell viability or their doubling time even at 200 µM levels.
Sinónimos : Fucosyltransferase Inhibitor, 2F-Peracetyl-Fucose - Calbiochem; (3S,4R,5R,6S)-3-fluoro-6-methyltetrahydro-2H-pyran-2,4,5-triyl triacetate
Fórmula molecula r: C12H17FO7
Armazenamento : -20C
Embalagem : 1X10MG
Sinónimos : Fucosyltransferase Inhibitor, 2F-Peracetyl-Fucose - Calbiochem; (3S,4R,5R,6S)-3-fluoro-6-methyltetrahydro-2H-pyran-2,4,5-triyl triacetate
Fórmula molecula r: C12H17FO7
Armazenamento : -20C
Embalagem : 1X10MG