gamma-Secretase Inhibitor II – Calbiochem

Descrição detalhada : A cell-permeable, reversible and selective peptidomimetic inhibitor of gamma-secretase (IC50 = 13 µM for Abeta). Displays only weak inhibitory activity against calpain II (IC50 = 100 µM in a purified enzyme assay).Please note that the molecular weight for this compound is batch-specific due to variable water content., A cell-permeable, reversible and selective peptidomimetic inhibitor of gamma-secretase with an IC50 of 13 µM for the inhibition of amyloid beta-protein (Abeta) production in beta-amyloid precursor protein (APP)-transfected Chinese hamster ovary cells. Displays only weak inhibitory activity against calpain II (IC50 = 100 µM in a purified enzyme assay).
Sinónimos : gamma-Secretase Inhibitor II - Calbiochem; MW167
Fórmula molecula r: C33H57F2N5O9
Armazenamento : -20C
Embalagem : 1X1MG