Gc-globulin from human plasma

Descrição detalhada : Gc-Globulin, a member of the albumin superfamily, is the major plasma carrier of vitamin D and its metabolites. It is also, along with gelsolin, part of the extracellular actin scavenger system. Gc-globulin also binds monomeric actin (G-actin) with high affinity to scavenge actin released by necrotic cells, preventing its polymerization into filaments. Gc-globulin enhances the chemoattractant activity of C5a for inflammatory cells., Gc-globulin from human plasma is encoded by the gene GC, which is mapped to human chromosome 4q13.3., Gc-globulin or the vitamin D binding protein (DBP) is a 51-58 kDa multifunctional serum glycoprotein synthesized in large quantities by primarily in the liver. It is a member of the albumin gene family and has the characteristic multiple disulfide-bonded, triple domain structure.
Sinónimos : DBP; Group-Specific Component; Vitamin D Binding Protein
Armazenamento : -20C
Embalagem : 1X1MG