Glucose Transporter Inhibitor III, STF-31 – Calbiochem

REF : 351801-10MG
Marca : Sigma-Aldrich
Descrição :Glucose Transporter Inhibitor III, STF-31 - Calbiochem The Glucose Transporter Inhibitor III, STF-31 controls the biological activity of Glucose Transporter.
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Descrição detalhada : A cell-permeable sulfonamide that selectively inhibits the growth of VHL-deficient renal cell carcinomas (RCCs) dose-dependently (0-5 µM) by directly targeting glucose transporter 1 (GLUT1), which is up-regulated by HIF (hypoxia-inducible factor) transcription factor in VHL-deficient cells. It elicits decreased oxidative phosphorylation associated with aerobic glycolysis and leads to necrosis, which is consistent with the effect induced by GLUT1 RNA interference. It does not bind to other glucose transporters, and does not inhibit a broad range of 50 tested kinases.
Sinónimos : Glucose Transporter Inhibitor III, STF-31 - Calbiochem; STF-31
Fórmula molecula r: C23H25N3O3S
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X10MG