Heat Shock Protein Inhibitor I – CAS 218924-25-5 – Calbiochem

Descrição detalhada : A benzylidine lactam compound that inhibits the induction of heat shock proteins, including HSP70, HSP72, and HSP105. Blocks the development of thermotolerance in a dose-dependent manner, but does not affect the thermosensitivity of nontolerant cells. Reported to be less toxic and more effective than Quercetin (Cat. No. 551600), and, unlike quercetin, it does not affect the activities of PKA, PKC, and PTK., A benzylidene lactam compound that blocks the induction of heat shock proteins HSP70, HSP72, and HSP105. Blocks the development of thermotolerance in a dose-dependent manner. Does not affect the thermosensitivity of nontolerant cells. Reported to be less toxic and more effective than Quercetin (Cat. No. 551600); and unlike Quercetin, it does not have an affect on the activities of PKA, PKC, or PTK.
Sinónimos : Heat Shock Protein Inhibitor I - CAS 218924-25-5 - Calbiochem; KNK437, N-Formyl-3,4-methylenedioxy-benzylidine-gamma-butyrolactam, Hsp70 Induction Inhibitor I; KNK437, N-Formyl-3,4-methylenedioxy-benzylidine-gamma-butyrolactam, Hsp70 Induction Inhibitor I
Fórmula molecula r: C13H11NO4
Armazenamento : -20C
Embalagem : 1X5MG