HepaRG(TM) 5F Control Cells

Descrição detalhada : HepaRG is a human hepatoma cell line. The cells possess a pseudodiploid karyotype and have been characterized as an oval ductular bipotent hepatic cell line as they have the ability to differentiate into both biliary and hepatocyte lineages in the presence of DMSO. HepaRG cells express the major xenobiotic sensors (PXR, CAR and AhR), drug transporters, phase I and II drug metabolizing enzymes as well as key hepatic transcription factors involved in stress response pathways., This product consists of ZFN engineered HepaRG 5F clone control cells. They are intended for use as both control cells for HepaRG(TM) knockout cells as well as for a wide variety of liver cell based assays. Hepa RG cells display hepatocyte-like functions and can be a replacement to primary human hepatocytes in a number of drug metabolism, disposition and genotoxicity studies.
Sinónimos : Human hepatocyte cells
Armazenamento : -196C
Embalagem : 1X1VL