Histamine, Free Base – CAS 51-45-6 – Calbiochem

Descrição detalhada : A potent vasodilator found in normal tissues and blood. Activates nitric oxide synthase., A potent vasodilator found in normal tissues and blood. Formed by the decarboxylation of L-histidine. Activates nitric oxide synthase (NOS), resulting in the release of nitric oxide. Activation of histamine H1 receptors leads to Ca2+ mobilization; whereas, histamine H2 receptor activation stimulates adenylate cyclase activity in neurons. Inhibits the synthesis of IL-2 and γ-IFN in peripheral blood mononuclear cells and lipopolysaccharide-induced synthesis of TNF-α in monocytes via H2 receptor activation., A potent vasodilator found in normal tissues and blood. Activates nitric oxide synthase. Formed by the decarboxylation of L-histidine. Activation of histamine H1 receptors leads to Ca2+ mobilization, whereas histamine H2 receptor activation stimulates adenylate cyclase activity in neurons. Stimulated time- and concentration-dependent increase in p38 and p42/p44 MAP kinases in DDT(1) MF2 cells.
Sinónimos : Histamine, Free Base - CAS 51-45-6 - Calbiochem
Fórmula molecula r: C5H9N3
Armazenamento : 2-8C; 2-8C; 2-8C; 2-8C
Embalagem : 1X1GM